Identification of key eRNAs for intervertebral disc degeneration by integrated multinomial bioinformatics analysis
Abstract Background Intervertebral disc degeneration (IVDD) is a common degenerative condition leading to abnormal stress distribution under load, causing intervertebral stenosis, facet joint degeneration, and foraminal stenosis.Very little is known about the molecular mechanism of eRNAs in IVDD.Methods Gene expression profiles of 38 annulus disc s